ChIP-on-chip is a technology that combines chromatin immunoprecipitation ('ChIP') with DNA microarray (\"chip\"). Like regular ChIP, ChIP-on-chip is used to investigate interactions between proteins and DNA in vivo. Specifically, it allows the identification of the cistrome, the sum of binding sites, for DNA-binding proteins on a genome-wide basis. Whole-genome analysis can be performed to determine the locations of binding sites for almost any protein of interest. As the name of the technique suggests, such proteins are generally those operating in the context of chromatin. The most prominent representatives of this class are transcription factors, replication-related proteins, like origin recognition complex protein (ORC), histones, their variants, and histone modifications.
"}{"type":"standard","title":"Yasuharu Suematsu","displaytitle":"Yasuharu Suematsu","namespace":{"id":0,"text":""},"wikibase_item":"Q11519742","titles":{"canonical":"Yasuharu_Suematsu","normalized":"Yasuharu Suematsu","display":"Yasuharu Suematsu"},"pageid":42336629,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/0/07/Dr._Yasuharu_Suematsu.jpg/330px-Dr._Yasuharu_Suematsu.jpg","width":320,"height":370},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/0/07/Dr._Yasuharu_Suematsu.jpg","width":510,"height":589},"lang":"en","dir":"ltr","revision":"1289082405","tid":"e37cef69-2a6a-11f0-a7a9-3628a1c35c59","timestamp":"2025-05-06T11:11:42Z","description":"Japanese scientist","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Yasuharu_Suematsu","revisions":"https://en.wikipedia.org/wiki/Yasuharu_Suematsu?action=history","edit":"https://en.wikipedia.org/wiki/Yasuharu_Suematsu?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Yasuharu_Suematsu"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Yasuharu_Suematsu","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Yasuharu_Suematsu","edit":"https://en.m.wikipedia.org/wiki/Yasuharu_Suematsu?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Yasuharu_Suematsu"}},"extract":"Yasuharu Suematsu is a Japanese electrical engineer whose work has been associated with developments in optical fiber communication technology. His research on dynamic single-mode lasers has been cited in several academic and technical studies. Suematsu holds the position of professor emeritus at the Institute of Science Tokyo.","extract_html":"
Yasuharu Suematsu is a Japanese electrical engineer whose work has been associated with developments in optical fiber communication technology. His research on dynamic single-mode lasers has been cited in several academic and technical studies. Suematsu holds the position of professor emeritus at the Institute of Science Tokyo.
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